Charmed (1998)

S2E16 Murphy's Luck

Title: Murphy's Luck Plot: Following Prue's heroic intervention to save a woman from taking her own life, a Darklighter retaliates by casting a spell that plunges her into a deep despair. This dark curse threatens not only her well-being but also her very existence, as Prue battles the oppressive sadness that risks consuming her entirely.