Get Smart (1965)

S5E11 Age Before Duty

Max is shocked when his youthful informant unexpectedly passes away from old age. In a meeting with CONTROL Agent Carruthers, he discovers that Carruthers, despite being just 28, is also on the brink of death from rapid aging. This alarming trend continues as more agents fall victim to a KAOS innovation known as Dorian Gray Paint, which accelerates aging when applied to their portraits. As a result, Max, now 99, along with the Chief, are transformed into elderly versions of themselves just before they manage to pinpoint the location of the KAOS headquarters.