Malcolm in the Middle (2000)

S4E10 If Boys Were Girls

After witnessing a chaotic fight among her sons, a pregnant Lois reflects on the challenges of raising another rowdy child. This leads her to imagine a world where her mischievous boys have become well-mannered daughters. In her daydream, Malcolm is now Mallory, Reese has transformed into Renee, and Dewey is reimagined as Daisy.